Generation of functional antibodies for mammalian membrane protein crystallography
نویسندگان
چکیده
منابع مشابه
High-Efficiency Screening of Monoclonal Antibodies for Membrane Protein Crystallography
Determination of crystal structures of membrane proteins is often limited by difficulties obtaining crystals diffracting to high resolution. Co-crystallization with Fab fragments of monoclonal antibodies has been reported to improve diffraction of membrane proteins crystals. However, it is not simple to generate useful monoclonal antibodies for membrane protein crystallography. In this report, ...
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ژورنال
عنوان ژورنال: Current Opinion in Structural Biology
سال: 2013
ISSN: 0959-440X
DOI: 10.1016/j.sbi.2013.04.007